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Contact Information

301-827-8617
6701 Democracy BLVD
Building: Democracy I, Suite 800
Bethesda MD 20892

Summary

Deepti Bajpai, Ph.D. was born and educated in India, receiving her Ph.D. degree from All India Institute of Medical Sciences in 2014. After that, she worked as a research associate and then ICMR centenary postdoctoral fellow in India. She joined Dr. Maria Morasso's lab in 2017 as a visiting fellow. Her research focuses on the role of DLX3 in modulating the signaling pathways in keratinocytes, which is crucial to epidermal differentiation control and cutaneous carcinogenesis.

Research Statement

Epidermal homeostasis results from a coordinated control of keratinocyte cell cycle and differentiation with an alteration of this balance leading to cancer. Dr. Bajpai's current research focuses on identifying the tumor-suppressive role of DLX3 in cutaneous squamous cell carcinoma. She utilizes various mouse models and a combination of transcriptomic and bioinformatic analysis to identify DLX3-dependent networks regulating squamous tumorigenesis.

Scientific Publications

Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway.

Bajpai D, Mehdizadeh S, Uchiyama A, Inoue Y, Sawaya A, Overmiller A, Brooks SR, Hasneen K, Kellett M, Palazzo E, Motegi SI, Yuspa SH, Cataisson C, Morasso MI
Oncogene.
2021 May;
40(21).
doi: 10.1038/s41388-021-01802-9
PMID: 33947961

Single nucleotide polymorphisms in the DNA repair genes in HPV-positive cervical cancer.

Bajpai D, Banerjee A, Pathak S, Thakur B, Jain SK, Singh N
Eur J Cancer Prev.
2016 May;
25(3).
doi: 10.1097/CEJ.0000000000000159
PMID: 25812040

Decreased expression of DNA repair genes (XRCC1, ERCC1, ERCC2, and ERCC4) in squamous intraepithelial lesion and invasive squamous cell carcinoma of the cervix.

Bajpai D, Banerjee A, Pathak S, Jain SK, Singh N
Mol Cell Biochem.
2013 May;
377(1-2).
doi: 10.1007/s11010-013-1569-y
PMID: 23435956

Serum one-carbon metabolites and risk of cervical cancer.

Pathak S, Bajpai D, Banerjee A, Bhatla N, Jain SK, Jayaram HN, Singh N
Nutr Cancer.
2014;
66(5).
doi: 10.1080/01635581.2014.916318
PMID: 24848140

Influence of Morinda citrifolia (Noni) on Expression of DNA Repair Genes in Cervical Cancer Cells.

Gupta RK, Bajpai D, Singh N
Asian Pac J Cancer Prev.
2015;
16(8).

Education

Doctor of Philosophy (Ph.D.) Biochemistry, (2010-2014) 
All India Institute of Medical Sciences, New Delhi, India.

Master of Science, Biotechnology, (2006-2008)
CSJMU University, Kanpur, Uttar Pradesh, India.

Bachelor of Science, Zoology, Botany and Chemistry (2003-2006)
CSJMU University, Kanpur, Uttar Pradesh, India.

Experience

Postdoctoral Fellow (October 2017-Present)
Laboratory of Skin Biology, NIAMS, NIH, Bethesda, USA

ICMR Postdoctoral Fellow (May 2016-June 2017)
National Institute of Pathology, Safdarjung Hospital, New Delhi

Research Associate (RA), (April 2014-July 2015)
Department of Biochemistry, AIIMS, New Delhi, India

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