Summary
Edward W. Cowen, M.D., M.H.Sc., leads the NIH Dermatology Consultation Service, conducts independent and collaborative research, and oversees the continuing medication education-accredited Dermatology Grand Rounds, Branch Clinical Fellowship and resident education programs. He is an internationally recognized expert in cutaneous graft-versus-host disease and serves as Director on the American Board of Dermatology as well as on the Editorial Board of JAMA Dermatology.
Research Statement
Dr. Cowen’s primary interests include chronic graft-versus-host disease (GVHD), primary immunodeficiency, autoinflammatory skin disease, cancer genodermatoses, and adverse drug reactions. As a founding member of the NIH chronic GVHD program, Dr. Cowen has authored more than 50 original manuscripts and chapters relating to the disease. Novel discoveries include the first identification of total body irradiation as a risk factor for skin fibrosis in chronic GVHD, the first comprehensive description of GVHD-associated angiomatosis, and the first link between voriconazole exposure and squamous cell carcinoma in allogeneic hematopoietic cell transplant recipients. Current research interests include novel treatments for skin fibrosis and objective measurement tools to assess disease activity and response.
Dr. Cowen also participates in the NIH Undiagnosed Disease program and has been involved in the description of several novel syndromes in collaboration with other NIH investigators, including deficiency of the IL-1 receptor antagonist (DIRA), GATA2 deficiency, ADA2 deficiency, cutaneous skeletal hypophosphatemia syndrome, and SAVI syndrome.
Scientific Publications
Education
Pennsylvania State College of Medicine
M.D.
Duke University
M.S., Health Sciences in Clinical Research
Cornell University
B.S., Biology
Experience
Acting Chief
Dermatology Branch, NIAMS, NIH
Head
Dermatology Consultation Service, NIH (2009 – present)
Senior Clinician
Dermatology Branch, NIAMS, NIH (2013)
Senior Staff
Dermatology Branch,
NCI, NIH (2004 – 2009)
Adjunct Faculty
Uniformed Services University of the Health Sciences and Georgetown University
Fellowship in Clinical Research
Dermatology Branch, NCI, NIH
Residency in Dermatology, Chief Resident
University of Rochester