The Community Research and Care Branch is a site of supervised training for rheumatology fellows and permits the evaluation and treatment of subjects who are members of the minority community. Our protocol aims to facilitate understanding of the pathogenesis and natural history of rheumatic diseases in this community. Patients are evaluated with a standard history and physical examination.
The Cutaneous Development and Carcinogenesis Section studies the signaling pathways such as Hedgehog signaling that regulate the development and maintenance of normal skin, and the changes in these signals that occur during the formation of skin cancer. Our investigations include studying the specification and maintenance of cell lineages in the skin, as well as studying the regulation of stem cells in the skin, and using mouse genetics to model carcinogenesis in the skin.
The Cutaneous Microbiome and Inflammation section is focused on studying the skin microbiome in healthy individuals with the goal of expanding our understanding of host-microbe interactions. Previous work has investigated the diversity and distrubution of bacterial and fungal skin communities in healthy adults.
Through the Dermatology Consultation Service at the NIH Clinical Center, patients with a variety of rare diseases with cutaneous manifestations are evaluated. In addition, patients who experience adverse reactions to experimental therapeutic agents or manifest unrelated skin conditions while at the NIH are evaluated and treated. Dermatology Branch clinical fellows, fellows from other NIH Institutes, and visiting dermatology residents from around the country receive training on the Dermatology consult service.
The mission of the Genomic Technology Unit is to help NIAMS investigators solve highly diverse biological and biomedical research questions by providing a diverse portfolio of sequencing services as well as consultation and training for researchers with specific needs or challenging problems. The core is a state-of-the-art laboratory facility equipped with the latest DNA sequencing and library preparation technologies.
The Office of Science and Technology (OST) is responsible for NIAMS Labs core facilities. It provides and develops new technologies, advises the Scientific Director, Lab and Branch Chiefs, and other key officials on science and technology. OST initiates collaborative, cooperative and service activities that facilitate the conduct of science and coordinates the core technological facilities of the Intramural Research Program.