Portrait of Kan Jiang.

Contact Information

301-594-3155
9000 Rockville Pike
Building 50, Room 1140
Bethesda MD 20892

Media Resources

Summary

Dr. Jiang received her Ph.D. from Aachen University in Germany and obtained her post-doctoral training at NCI and NIAMS, where she focused on the roles of transcription factors, chromatin regulators and epigenetic markers of immune cells. In 2018 she joined the Biodata Mining and Discovery Section.

Research Statement

Studies of Functions of genomics, epigenomics and transcriptomics through Next Generation Sequencing methods and approaches, focusing on CHIP-Seq, RNA-Seq, ATAC-Seq and HiC.

Scientific Publications

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.

Mistry P, Nakabo S, O'Neil L, Goel RR, Jiang K, Carmona-Rivera C, Gupta S, Chan DW, Carlucci PM, Wang X, Naz F, Manna Z, Dey A, Mehta NN, Hasni S, Dell'Orso S, Gutierrez-Cruz G, Sun HW, Kaplan MJ
Proc Natl Acad Sci U S A.
2019 Dec 10;
116(50).
doi: 10.1073/pnas.1908576116
PMID: 31754025

A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans.

Tsai PF, Dell'Orso S, Rodriguez J, Vivanco KO, Ko KD, Jiang K, Juan AH, Sarshad AA, Vian L, Tran M, Wangsa D, Wang AH, Perovanovic J, Anastasakis D, Ralston E, Ried T, Sun HW, Hafner M, Larson DR, Sartorelli V
Mol Cell.
2018 Jul 5;
71(1).
doi: 10.1016/j.molcel.2018.06.008
PMID: 29979962

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

Yang XP, Jiang K, Hirahara K, Vahedi G, Afzali B, Sciume G, Bonelli M, Sun HW, Jankovic D, Kanno Y, Sartorelli V, O'Shea JJ, Laurence A
Sci Rep.
2015 Jun 19;
5().
doi: 10.1038/srep10643
PMID: 26090605

Regulation of the MAD1 promoter by G-CSF.

Jiang K, Hein N, Eckert K, Lüscher-Firzlaff J, Lüscher B
Nucleic Acids Res.
2008 Mar;
36(5).
doi: 10.1093/nar/gkn002
PMID: 18203738

Education

  • Aachen University (RWTH), Aachen, Germany, Ph.D.
  • Huazhong University of Science and Technology, China, M.S.
  • Tongji Medical University, China, B.S. & M.D.

Experience

  • Staff Scientist BMDS, OST, NIAMS, NIH
  • Postdoctoral Fellow NCI & NIAMS, NIH
  • Resident Wuhan Children’s Hospital, Hubei Province, China
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