Research Progress Related to Psoriasis

Researchers work to understand what causes psoriasis, to identify new treatment strategies, and to uncover other conditions associated with the disease. Following are some examples of the types of studies they are working on.

• Researchers are performing molecular and genetic analyses of people with the disease to enhance the understanding of how psoriasis starts and help identify new treatment targets.
• The NIH-supported Accelerating Medicines Partnership® Autoimmune and Immune-Mediated Diseases (AMP® AIM) Program aims to deepen our understanding of the cellular and molecular interactions that lead to inflammation and autoimmune diseases, including psoriasis and psoriatic arthritis.
• Scientists are studying the makeup of the human microbiome in people with psoriasis and how it may affect psoriatic disease outcomes.
• Since people with psoriasis have a greater risk of other diseases such as diabetes, obesity, and liver disease, researchers are trying to find out if there are shared genetic risk factors among these diseases.
• Scientists are focusing on patients' satisfaction with psoriasis therapies to help inform shared decision-making between clinicians and patients, predict treatment adherence, improve the likelihood of long-term treatment success, and impact the design of future dermatology therapeutic studies.