Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions
http://niamsdeva.iqscloud.net/node/14436
Inflammatory conditions can cause symptoms like fevers, arthritis, and rash. Systemic juvenile idiopathic arthritis (sJIA) is one of these conditions. So is adult-onset Still s disease (AOSD). Their causes are unknown. Researchers want to learn more about these conditions. This includes genetic changes and environmental factors.
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases
http://niamsdeva.iqscloud.net/node/14431
Natural History of Inflammatory Muscle Diseases
http://niamsdeva.iqscloud.net/node/14426
This is an observational study to characterize the different types of inflammatory myopathies, understand their etiology, pathogenesis, prognosis, and response to different treatments.
Effects of Treatments on the Microbiome in Healthy Volunteers and Patients With Atopic Dermatitis
http://niamsdeva.iqscloud.net/node/14421
Atopic dermatitis, or eczema, is a chronic skin disorder. The use of antibiotics has revolutionized medicine, yet the impact of antimicrobials on the human microbiome is incompletely understood. This study aims to characterize microbiome alterations in healthy adult volunteers and patients with atopic dermatitis after antimicrobial treatments.
Studies of Dermatologic Diseases-Biospecimen Acquisition Protocol
http://niamsdeva.iqscloud.net/node/14411
Skin diseases represent one of the most common medical problems in the United States, affecting 1 in 3 people at any given time. This study aims to procure biologic samples for exploratory cellular, molecular, genetic and genomic biological studies from subjects with dermatologic conditions, subjects at risk for developing dermatologic conditions and healthy volunteers in the support of NIH biomedical studies.
Compassionate Use Treatment Protocol I4V-MC-JAGA: Treatment of Conditions Expected to Benefit From JAK 1/2 Inhibition: CANDLE, CANDLE-Related Conditions, SAVI and Severe Juvenile Dermatomyositis
http://niamsdeva.iqscloud.net/node/14406
The Requesting Physician/Investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.
The Role of PPAR-Gamma Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)
http://niamsdeva.iqscloud.net/node/14396
The Natural History of Coronavirus Disease (COVID-19) in Systemic Autoimmune Diseases; An Observational Prospective Study
http://niamsdeva.iqscloud.net/node/14391
Study of Systemic Lupus Erythematosus
http://niamsdeva.iqscloud.net/node/14381
This study enrolls patients with systemic lupus erythematosus. The goal is to identify clinical subsets of patient that might aid in understanding progress and determining appropriate therapies. The goals of this research study are to evaluate patients thought to have the disease to better understand how the disease begins and how it affects patients. Secondly, to follow patients during the course of the disease to understand how the disease changes over time and the effects of standard treatments.
