Hypodermal macrophages play an important role in infection outcomes in the skin.  

Recombinant amphiregulin could be a potential therapeutic agent for cutaneous I/R injury.

CD271 could be a promising pharmaceutical target for the treatment of cutaneous squamous cell carcinoma.

The study identifies several novel SLE susceptibility genes in an ancestrally diverse childhood-onset lupus cohort.

The modified clinical algorithm allows for faster diagnosis and treatment of children with APECED syndrome.

Early diagnosis and interventions have improved the quality of life for STAT3DN patients.

The study characterizes the colonization of eukaryotic RNA viruses in RAG-deficient patient population and also demonstrates the importance of these patients as potential reservoirs of viral persistence and evolution.

The study reports the use of urine as a biomarker source for JDM.

A physician should be aware of the ophthalmological effects of autoinflammatory diseases, particularly this new entity called the VEXAS syndrome.

According to the report, mutations of UBA1 in hematopoietic stem cells appear to cause abnormal inflammation and myeloid predominance in VEXAS syndrome.